The CheckMate™/Flexi ® System is patterned on the yeast two-hybrid system with one protein of interest ('X') fused to a DNA-binding domain and the other protein ('Y') fused to a transcriptional activation domain.
The system can allow mammalian protein expression and post-translational modification studies in an environment mimicking the native cell milieu. This system can also be used to generate stable cell lines for cell-based assays. The CheckMate™/Flexi® System is designed to confirm, validate and study suspected interactions between two proteins or domains.
